Scenario one: Under high-light (HL) stress, the plant nuclear-organellar communication is critical for survival, minimizing the photooxidative damage and enhancing resilience. Interestingly, this includes highly complex interplay of retrograde and anterograde signals in fine-tuning the plant response to stress.
Scenario two: Long non-coding RNAs (lncRNAs) have been observed to interact with diverse molecules, such as DNA, RNA, and proteins, allowing these transcripts to function distinctly at various levels of gene expression regulation. Interestingly, the interaction partners of lncRNAs can change depending on their localization within the cell. In mammals, lncRNAs have been found to localize in organelles and macromolecular structures such as p-bodies and stress granules.
Based on the above scenarios, we started investigating lncRNAs at the sub-cellular levels in Arabidopsis in HL stress to understand if they could be involved in the nuclear-organellar cross-talk, fine-tuning expression of specific genes for optimum response.